By therefore doing, hopefully the relevant chemical substance space at different sirtuin dynamic sites could possibly be even more comprehensively explored, and more powerful and selective cyclic peptide-based SIRT5 inhibitors harboring the SIRT5 inhibitory warhead N-carboxyethyl-thiocarbamoyl-lysine could possibly be found also. ? Open in another window Scheme 1 The solid … Continue reading By therefore doing, hopefully the relevant chemical substance space at different sirtuin dynamic sites could possibly be even more comprehensively explored, and more powerful and selective cyclic peptide-based SIRT5 inhibitors harboring the SIRT5 inhibitory warhead N-carboxyethyl-thiocarbamoyl-lysine could possibly be found also